Study of Muscle Profile in Elderly Individuals from Rural Populations in Western Cameroon
Objective: This study aims to assess the impact of aging on muscle balance in elderly individuals across five rural localities in Western Cameroon (Bafang, Bafoussam, Baham, Bandjoun, and Dschang). It explores variations in muscle biochemical parameters based on age, sex, and local specificities.
Methodology: A cross-sectional study was conducted among subjects aged 50 years and older. Serum concentrations of creatinine, creatine kinase (CK), and alkaline phosphatase (ALP) were measured. Participants were categorized by age groups and sex to analyze the biological trends of muscle aging.
Results: Data analysis revealed an increased prevalence of hypocreatinemia, hypoCKemia, and hyperphosphatasemia with aging, particularly after 70 years. These alterations were more pronounced in women and varied across localities. The findings suggest an association between these biochemical abnormalities and environmental factors such as dietary habits, physical activity levels, and living conditions.
Conclusion: Aging is associated with a progressive alteration of muscle biomarkers, highlighting an increased risk of sarcopenia in the elderly population. These findings underscore the importance of targeted preventive interventions based on regional specificities and identified risk factors.
Keywords: Aging, muscle balance, creatinine, creatine kinase, alkaline phosphatase, physical activity, nutrition, environmental factors.
