Variations in Hematological Parameters Associated with Aging in the Western Region of Cameroon
Background : Aging induces physiological changes affecting various body systems, including hematological parameters. This study examines blood cell variations (white blood cells, red blood cells, lymphocytes, monocytes, granulocytes, hemoglobin, hematocrit, and platelets) across different localities in Western Cameroon, considering sex and age differences.
Methods : A cross-sectional study was conducted in five localities (Bafang, Bafoussam, Baham, Bandjoun, and Dschang), involving 768 participants aged ≥50 years. Blood samples were collected and analyzed in the clinical biology laboratory of Bafoussam Regional Hospital. Statistical analyses included Pearson correlation tests and cross-tabulation analysis using SPSS and XLSTAT.
Results : Significant variations in leukocyte, erythrocyte, and platelet counts were observed, with a higher prevalence of leukopenia, anemia, and thrombocytopenia in older populations, particularly among men (p < 0.05). The findings highlight the impact of aging on hematological parameters, suggesting potential health implications.
Conclusion : Aging is associated with significant declines in hematological parameters, with sex- and locality-based differences. Further studies should investigate potential interventions to mitigate age-related hematological disorders in this population.
Keywords : blood cells, leukopenia, anemia, thrombocytopenia, aging
