The Inhibition of Moringa Leaves Extract (Moringa oleifera Lamk.) to the Growth of Porphyromonas gingivalis
Background: Periodontal disease is one of the oral health problems with a prevalence of 50 % of the number of adults worldwide. The most common periodontal disease is chronic periodontitis with the main cause being plaque bacteria in the gingival sulcus. The most dominant bacteria is Porphyromonas gingivalis. Moringa is a plant used as an herbal medicine, especially the leaves with antibacterial properties because they contain flavonoids, saponins, tannins, alkaloids, triterpenoids, and terpenoids. Objective: This study aimed to determine the presence or absence of the inhibitory ability of moringa leaf extract and the largest concentration of moringa leaf extract in inhibiting the growth of P. gingivalis. Material and Methods: The method used was the paper disc diffusion method. 24 samples were divided into 6 groups. The treatment group was given various concentrations (100%, 75%, 50%, and 25%) of moringa leaf extract, the positive control group was given 0.2% chlorhexidine gluconate and the negative control group was given aquadest. The disc which spilled by various concentrations of moringa leaf extracts, 0.2% chlorhexidine, and aquadest was placed on a medium which has been inoculated by P. gingivalis, then incubated at 37ºC for 24 hours. The inhibition zone was measured using a digital caliper. Results: Moringa leaves extract 25 %, 50 %, 75 %, and 100 % had different inhibitory power against P. gingivalis, with a Kruskal-Wallis test significance value of p=0,00. Conclusions: Moringa leaf extract has an inhibitory effect on P. gingivalis. 75 and 100% of moringa leaf extract has the highest antibacterial inhibition zone.
Keywords: Inhibitory, Moringa Leaf, Periodontitis, Porphyromonas gingivalis
