A comparison of survival between HIV- infected and HIV- uninfected cervical cancer patients on chemo radiotherapy
This study compares the survival rates and treatment outcomes of HIV-infected versus HIV-uninfected cervical cancer patients undergoing chemoradiotherapy. A total of 158 patients (60 HIV-positive and 98 HIV-negative) were analyzed for survival rates, treatment toxicity, and associated factors. Significant differences in overall survival and toxicity were observed between the two groups. The 5-year overall survival (OS) rate was 50% for HIV-positive patients compared to 65% for HIV-negative patients (p = 0.007). HIV-positive patients experienced greater toxicity (p = 0.0259) and had worse survival outcomes. Factors including age, initial hemoglobin levels, and radiation dose were found to impact survival irrespective of HIV status.
